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KMID : 1004620130190010045
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Clinical Nursing Research
2013 Volume.19 No. 1 p.45 ~ p.56
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The Effects of the Individual Application of Low Sodium Dialysate on Weight Gain, Blood Pressure, and Intradialytic Side Effects in Patients on Maintenance Hemodialysis
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Song Ji-Sook
Kim Eun-Sook
Lee Yu-Na
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Abstract
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Purpose: The purpose of this study is to identify the effect of low sodium dialysate (LSD) rather than conventional
dialysate on interdialytic weight gain (IWG), blood pressure (BP), and intradialytic side-effects (ISEs) in patients on maintenance hemodialysis (HD).
Methods: The study was performed in 43 patients, who were treated in the university hospital over 8 weeks. Each participant’s serum sodium set point was measured using dialysate sodium 140 mEq/L during the first 4 weeks. For the next 4 weeks dialysate sodium concentrate (134,136,and138 mEq/L) was provided to each participant but only to an experimental group (EG) (n=22) based on the individual set point, although 140 mEq/L dialysate was given to all of the control group (CG) (n=21). Consequently, outcomes including IWG, BP, and ISE were evaluated.
Results: In EG, difference of pre- HD SBP (p=.047) and post-HD serum sodium (p=.006) were significantly decreased compared to CG. Also, ISEs was not more frequent in EG. However, the differences were not statistically significant, IWG (kg & %), pre-HD DBP, post-HD SBP & DBP, and serum osmolality in EG.
Conclusion: Individual application of LSD in patients on maintenance hemodialysis is beneficial to decrease pre-HD SBP and post-HD serum sodium without increasing ISE. Therefore, LSD can be better treatment than conventional dialysate.
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KEYWORD
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Dialysis solutions, Hemodialysis, Weight gain, Blood pressure
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